Description

2-[(8-Chloromethylnaphthalen-1-Yl)Thio]Acetic Acid is a specialized organic compound featuring a naphthalene core functionalized with chloromethyl and thioacetic acid groups, making it a valuable synthetic intermediate. This compound matters for its role in facilitating complex molecular construction, particularly in the synthesis of advanced pharmaceutical agents and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized polymers or organic electronic materials.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological processes due to its reactive chloromethyl group.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing complex ligands used in catalytic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	2-[(8-Chloromethylnaphthalen-1-Yl)Thio]Acetic Acid
CAS No.	64059-42-3
Molecular Formula	C₁₃H₁₁ClO₂S
Molecular Weight	266.74 g/mol
Synonyms	2-[(8-Chloromethyl-1-naphthyl)thio]acetic acid; Acetic acid, 2-[(8-chloromethyl-1-naphthalenyl)thio]-; 1-Naphthalenethiol, 8-(chloromethyl)-, S-acetate; 8-Chloromethyl-1-naphthalenethiol acetate; (8-Chloromethylnaphthalen-1-ylthio)acetic acid; 2-((8-(Chloromethyl)naphthalen-1-yl)thio)acetic acid
EINECS	Contact for details

Quality Control

Our 2-[(8-Chloromethylnaphthalen-1-Yl)Thio]Acetic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.