Description

3-Tosylpropane-1,2-Diol is a versatile organic building block and synthetic intermediate characterized by its tosyl-protected diol functionality. This compound is valued for its role in facilitating selective chemical transformations, particularly in the synthesis of complex molecules where controlled reactivity is paramount. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected alcohol groups.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Polymer Chemistry: Serves as a monomer or chain modifier in the production of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, including natural product analogs.
• Ligand and Catalyst Preparation: Useful precursor for synthesizing chiral ligands or metal-organic complexes used in asymmetric catalysis.
• Cross-coupling Reactions: The tosyl group can act as a leaving group in various metal-catalyzed coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	3-Tosylpropane-1,2-Diol
CAS No.	63991-87-7
Molecular Formula	C10H14O4S
Molecular Weight	230.28 g/mol
Synonyms	1,2-Propanediol, 3-(4-methylphenyl)sulfonyl-; 3-(p-Tolylsulfonyl)-1,2-propanediol; 3-(Tosyloxy)-1,2-propanediol; 2-Hydroxy-3-(4-methylphenylsulfonyl)-1-propanol; 3-O-Tosyl-1,2-propanediol; 1,2-Dihydroxy-3-(p-toluenesulfonyloxy)propane; Glycidol 3-tosylate (hydrolyzed); TPD
EINECS	Contact for details

Quality Control

Our 3-Tosylpropane-1,2-Diol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity (IR), and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.