Description

4-Hydroxy-α-(Methylaminomethyl)Cyclohexanemethanol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both hydroxy and methylaminomethyl functional groups on a cyclohexane ring, makes it a valuable precursor for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new chemical entities, particularly for applications in medicinal chemistry and asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Ligand: Serves as a precursor for synthesizing chiral ligands used in enantioselective catalysis to produce optically pure compounds.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and other specialty fine chemicals requiring stereochemical control.
• Bioconjugate Chemistry: The functional groups allow for derivatization and linkage in the development of bioconjugates and prodrugs.
• Academic & Industrial Research: Used as a standard or building block in methodological studies and process chemistry optimization within R&D laboratories.

Basic Information

Product Name	4-Hydroxy-α-(Methylaminomethyl)Cyclohexanemethanol
CAS No.	63918-84-3
Molecular Formula	C9H19NO2
Molecular Weight	173.25 g/mol
Synonyms	4-Hydroxy-α-(methylaminomethyl)cyclohexanemethanol; (1R,4S)-4-Hydroxy-α-[(methylamino)methyl]cyclohexanemethanol; 4-Hydroxy-α-(methylaminomethyl)cyclohexanemethanol; Cyclohexanemethanol, 4-hydroxy-α-(methylaminomethyl)-; Potential stereoisomer of Phendimetrazine intermediate; Chiral amino alcohol derivative; Amino cyclohexanol derivative
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-α-(Methylaminomethyl)Cyclohexanemethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for specified isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.