Description

2-Bromo-4-Chloro-1-Nitro-Benzene is a versatile halogenated nitrobenzene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of its bromo, chloro, and nitro functional groups, which allow for selective and sequential substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and halogen groups are modified to create bioactive compounds.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of complex organic dyes and colorants.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and other advanced functional molecules.
• Cross-Coupling Reactions: Acts as a substrate in Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions due to the reactive bromo substituent.
• Nucleophilic Aromatic Substitution: The nitro group activates the aromatic ring for substitution, making it valuable for introducing various nucleophiles.

Basic Information

Product Name	2-Bromo-4-Chloro-1-Nitro-Benzene
CAS No.	63860-31-1
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	1-Bromo-2-Chloro-5-Nitrobenzene; 2-Chloro-4-Bromonitrobenzene; 4-Chloro-2-Bromonitrobenzene; 2-Bromo-4-Chloronitrobenzene; Benzene, 2-bromo-4-chloro-1-nitro-; 5-Nitro-2-chlorobromobenzene; 2-Chloro-1-bromo-5-nitrobenzene; 4-Chloro-2-bromo-1-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-1-Nitro-Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.