Description

Ethyl (2S)-2-Hydroxy-3-Methylbutanoate is a chiral ester valued for its specific stereochemistry and fruity, wine-like aroma profile. This compound is a critical building block and flavor/fragrance intermediate in high-value synthesis. It is primarily sought by manufacturers in the pharmaceutical, flavor & fragrance, and fine chemical industries for applications requiring precise enantiomeric purity.

Application

• Pharmaceutical Intermediate: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the (S)-configured hydroxy acid moiety.
• Flavor & Fragrance Ingredient: Serves as a key component in creating complex fruity, wine, or brandy notes for premium food flavorings and perfumery.
• Chiral Solvent or Auxiliary: Employed in specialized organic synthesis and resolution processes due to its stereogenic center.
• Chemical Research & Development: Utilized as a standard or starting material in academic and industrial R&D for method development and novel compound synthesis.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain enantiomerically pure agrochemicals.

Basic Information

Product Name	Ethyl (2S)-2-Hydroxy-3-Methylbutanoate
CAS No.	63674-18-0
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(S)-Ethyl 2-Hydroxy-3-methylbutyrate; Ethyl L-2-Hydroxy-3-methylbutyrate; (2S)-2-Hydroxy-3-methylbutanoic Acid Ethyl Ester; Ethyl (S)-2-Hydroxy-3-methylbutanoate; L-2-Hydroxy-3-methylbutyric Acid Ethyl Ester; Ethyl Obtusate; Ethyl (S)-Obtusate
EINECS	Contact for details

Quality Control

We supply Ethyl (2S)-2-Hydroxy-3-Methylbutanoate in various grades, including standard and high-purity enantiomeric excess (ee) grades suitable for demanding applications. Our products undergo rigorous quality testing to ensure compliance with industry standards, including chiral purity analysis. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area. Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.