Description

6,8-Bis(Acetylthio)Octanoic Acid Methyl Ester is a specialized sulfur-containing ester derivative of octanoic acid, serving as a critical synthetic intermediate and biochemical research tool. Its unique bifunctional thioester structure makes it valuable for constructing complex molecules and probing enzymatic pathways. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in advanced organic synthesis, medicinal chemistry, and the development of enzyme inhibitors or prodrugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting metabolic pathways.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies, especially for research involving lipoic acid analogs or thiol-disulfide exchange reactions.
• Organic Synthesis: Serves as a versatile reagent for introducing protected thiol functionalities into complex organic molecules.
• Prodrug Development: Investigated for its potential in designing prodrugs due to its metabolically labile acetylthio groups.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying cysteine proteases and other thiol-reactive enzymes.

Basic Information

Product Name	6,8-Bis(Acetylthio)Octanoic Acid Methyl Ester
CAS No.	63658-43-5
Molecular Formula	C13H22O4S2
Molecular Weight	306.44 g/mol
Synonyms	Methyl 6,8-Bis(acetylthio)octanoate; 6,8-Di(acetylthio)octanoic Acid Methyl Ester; Octanoic acid, 6,8-bis(acetylthio)-, methyl ester; Methyl 6,8-dithioacetoxyoctanoate; 6,8-Bis(acetylmercapto)octanoic Acid Methyl Ester; Lipoic Acid Derivative; DL-6,8-Bis(acetylthio)octanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 6,8-Bis(Acetylthio)Octanoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.