Description

3-o-Benzyl-4-(Hydroxymethyl-1,2-o-Isopropylidene)-α-D-Erythropentofuranose is a key protected carbohydrate intermediate, essential for the controlled synthesis of complex nucleoside analogs and other biologically active molecules. Its value lies in providing a versatile scaffold with orthogonal protecting groups, enabling precise and sequential chemical modifications in multi-step synthetic routes. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in antiviral, anticancer, and other nucleoside-based therapeutic agents.

Application

• Nucleoside Analog Synthesis: A critical building block for the preparation of modified nucleosides used in antiviral and anticancer drug discovery.
• Pharmaceutical Intermediates: Serves as a versatile precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Used in academic and industrial research to study glycosylation reactions and develop new synthetic methodologies.
• Oligonucleotide Synthesis: Acts as a protected sugar moiety for the construction of modified oligonucleotides for diagnostic and therapeutic applications.
• Glycoconjugate Preparation: Employed in the synthesis of glycoconjugates for biochemical and immunological studies.
• Chiral Pool Synthesis: Utilized as a chiral starting material for the asymmetric synthesis of natural products and other complex molecules.

Basic Information

Product Name	3-o-Benzyl-4-(Hydroxymethyl-1,2-o-Isopropylidene)-α-D-Erythropentofuranose
CAS No.	63593-03-3
Molecular Formula	C16H22O6
Molecular Weight	310.34 g/mol
Synonyms	1,2-O-Isopropylidene-3-O-benzyl-α-D-erythro-pentofuranose; 3-O-Benzyl-1,2-O-isopropylidene-α-D-erythro-pentofuranose; 3-O-Benzyl-1,2-O-isopropylidene-α-D-ribofuranose; 3-O-Benzyl-1,2-O-isopropylidene-α-D-xylofuranose (common misnomer based on erythro configuration); Benzyl-protected isopropylidene ribose derivative; Protected D-ribose derivative; 3-O-Bn-1,2-O-iPr-α-D-erythro-pentofuranose
EINECS	Contact for details

Quality Control

Our 3-o-Benzyl-4-(Hydroxymethyl-1,2-o-Isopropylidene)-α-D-Erythropentofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.