Description

8-Bromo-2,3-dihydrobenzo[1,4]dioxin-5-ylamine is a high-purity, functionalized benzodioxin derivative that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile aromatic amine handle with a fused dioxane ring and bromine substituent, enabling precise molecular construction for complex target molecules. Pharmaceutical, agrochemical, and material science researchers need it for developing novel active ingredients, ligands, and functional polymers where specific spatial and electronic properties are required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators that leverage its unique heterocyclic structure.
• Ligand Synthesis: Used in the preparation of chelating ligands for catalysis and metal-organic frameworks (MOFs) due to the amine and ether functionalities.
• Material Science: Monomer or functionalizing agent for creating specialty polymers, dyes, and organic electronic materials with tailored properties.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry and the development of biochemical tools.
• Academic & R&D: Serves as a valuable reagent in methodological organic chemistry research and discovery chemistry within university and industrial laboratories.

Basic Information

Product Name	8-Bromo-2,3-dihydrobenzo[1,4]dioxin-5-ylamine
CAS No.	63574-45-8
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	5-Amino-8-bromo-2,3-dihydro-1,4-benzodioxin; 8-Bromo-2,3-dihydro-1,4-benzodioxin-5-amine; 8-Bromo-5-amino-2,3-dihydro-1,4-benzodioxine; 5-Amino-8-bromo-2,3-dihydrobenzo[b][1,4]dioxine; 8-Bromo-2,3-dihydro-1,4-benzodioxin-5-ylamine; 63574-45-8; 8-Bromodihydrobenzodioxin-5-amine
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3-dihydrobenzo[1,4]dioxin-5-ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality assurance supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a controlled, dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.