Description

(3As)-3Aβ,4,6Aβ,7,9Aβ,9Bα-Hexahydro-3-Methylene-6,9-Dimethylazuleno[4,5-B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity and structural complexity. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its unique azulene-fused furanone scaffold.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting anti-inflammatory and anticancer pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive molecules based on the sesquiterpene lactone core.
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total or semi-synthesis of complex natural products and their analogs.
• Agrochemical Development: Potential precursor for developing new active ingredients with herbicidal or pesticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes to study specific biological processes and enzyme interactions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a structurally defined, high-value chiral intermediate.

Basic Information

Product Name	(3As)-3Aβ,4,6Aβ,7,9Aβ,9Bα-Hexahydro-3-Methylene-6,9-Dimethylazuleno[4,5-B]Furan-2(3H)-One
CAS No.	63569-76-6
Molecular Formula	C15H18O2
Molecular Weight	230.30 g/mol
Synonyms	3-Methylene-6,9-dimethylazuleno[4,5-b]furan-2(3H)-one, hexahydro-, (3aS,4S,6aS,7S,9aS,9bR)-rel-; rel-(3aS,4S,6aS,7S,9aS,9bR)-Hexahydro-3-methylene-6,9-dimethylazuleno[4,5-b]furan-2(3H)-one; Azuleno[4,5-b]furan-2(3H)-one derivative; Sesquiterpene lactone intermediate; 63569-76-6
EINECS	Contact for details

Quality Control

Our (3As)-3Aβ,4,6Aβ,7,9Aβ,9Bα-Hexahydro-3-Methylene-6,9-Dimethylazuleno[4,5-B]Furan-2(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.