Description

3-Fluoro-5-Bromo-2-Pentanone is a versatile halogenated ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and bromine substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel fluorinated and brominated drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the introduction of halogen atoms can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Employed to create tagged molecules for studying enzyme mechanisms and protein-ligand interactions due to its reactive ketone and halogen handles.
• Fluorine Chemistry: A valuable substrate for exploring new fluorination and halogen-exchange reactions in methodological organic chemistry research.

Basic Information

Product Name	3-Fluoro-5-Bromo-2-Pentanone
CAS No.	63141-04-8
Molecular Formula	C5H8BrFO
Molecular Weight	183.02 g/mol
Synonyms	5-Bromo-3-fluoro-2-pentanone; 2-Pentanone, 3-fluoro-5-bromo-; 3-Fluoro-5-bromopentan-2-one; 1-Bromo-3-fluoroacetone propyl ketone; α-Fluoro-γ-bromoethyl ethyl ketone
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Bromo-2-Pentanone is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical testing, including chromatography and spectroscopy, to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area, away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for extended stability. The container should be kept upright and securely sealed to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.