Description

Tetraethylammonium Fluoride Dihydrate is a versatile quaternary ammonium fluoride salt, serving as a powerful source of naked fluoride ions in organic synthesis. Its value lies in its dual functionality as a phase-transfer catalyst and a strong, non-nucleophilic base, enabling critical transformations under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity reagents for demanding synthetic protocols.

Application

• Nucleophilic Fluorination Reactions: A key reagent for introducing fluorine atoms into organic molecules, crucial for developing pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability.
• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, improving yields and efficiency in alkylation, esterification, and other industrial processes.
• Desilylation Agent: Efficiently cleaves silicon-protecting groups (e.g., TBDMS, TMS) in complex multi-step organic syntheses, particularly in peptide and nucleotide chemistry.
• Promoter for C-C Bond Formation: Used as a base to generate reactive carbanions in aldol, Michael addition, and other carbon-carbon coupling reactions.
• Electrolyte Additive: Investigated for use in specialty battery formulations and electrochemical applications due to its ionic conductivity and stability.
• Polymerization Catalyst: Acts as an initiator or catalyst in the synthesis of specific fluorinated polymers and other advanced polymeric materials.

Basic Information

Product Name	Tetraethylammonium Fluoride Dihydrate
CAS No.	63123-01-3
Molecular Formula	C8H20FN · 2H2O
Molecular Weight	177.25 g/mol (anhydrous basis)
Synonyms	TEA Fluoride Dihydrate; Tetraethylammonium Fluoride Hydrate; N,N,N-Triethylethanaminium Fluoride Dihydrate; Et4NF·2H2O; TBAF Analog (Tetraethyl); Fluorotetraethylammonium Dihydrate; Tetraethylammonium Fluoride 2-Hydrate
EINECS	Contact for details

Quality Control

Our Tetraethylammonium Fluoride Dihydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Water Content (KF)	18.0 - 22.0 %
Heavy Metals (as Pb)	≤ 10 ppm
Chloride (Cl)	≤ 0.1 %
Sulfate (SO4)	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.