Description

Butanamide, 2-Amino-3-Methyl-2-(1-Methylethyl)- is a specialized branched-chain amino acid derivative with a unique sterically hindered structure. This compound serves as a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex molecules with specific chiral and steric properties. It is primarily utilized by pharmaceutical research and fine chemical synthesis sectors for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate sterically hindered, non-proteinogenic amino acid motifs into peptides and peptide-like compounds to modulate biological activity and stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective synthesis.
• Agrochemical Research: Employed in the development of advanced pesticides and herbicides where specific stereochemistry influences efficacy.
• Material Science: Potential monomer or modifier for creating specialized polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Butanamide, 2-Amino-3-Methyl-2-(1-Methylethyl)-
CAS No.	63097-46-1
Molecular Formula	C8H17NO
Molecular Weight	143.23 g/mol
Synonyms	2-Amino-3-methyl-2-(1-methylethyl)butanamide; 2-Amino-3-methyl-2-isopropylbutyramide; L-Valinamide, 3-methyl-2-(1-methylethyl)- (8CI); 3-Methyl-2-(1-methylethyl)-L-valinamide; 2-Amino-2-isopropyl-3-methylbutyramide; Sterically hindered valine amide derivative; Amino-isopropyl-methyl-butyramide
EINECS	Contact for details

Quality Control

Our Butanamide, 2-Amino-3-Methyl-2-(1-Methylethyl)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, chiral analysis, NMR, and other relevant tests. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation or clumping. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.