Description

(R)-4-Propyldihydrofuran-2(3H)-One is a chiral lactone building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Flavor & Fragrance Industry: Serves as a precursor for the production of specific lactone-based aroma compounds.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems.
• Material Science: A monomer or building block for synthesizing specialized polymers with unique properties.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process development for chiral molecules.

Basic Information

Product Name	(R)-4-Propyldihydrofuran-2(3H)-One
CAS No.	63095-51-2
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	(R)-4-Propyl-γ-butyrolactone; (R)-4-Propylbutyrolactone; (R)-4-Propyl-dihydrofuran-2(3H)-one; (3R)-4-Propyloxolan-2-one; (R)-γ-Propyl-γ-butyrolactone; (R)-4-Propyl-2-oxotetrahydrofuran; (R)-4-Propyl-γ-valerolactone (common misnomer); (R)-4-Propyl-2-oxo-tetrahydrofuran
EINECS	Contact for details

Quality Control

Our (R)-4-Propyldihydrofuran-2(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing identity, purity (by GC/HPLC), enantiomeric excess (by chiral HPLC or GC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.