Description

3-Trifluoromethyl-Benzamidine Hcl is a high-purity organic building block featuring a benzamidine core substituted with a trifluoromethyl group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel therapeutic agents, including protease inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting various disease pathways.
• Protease Inhibitor Development: Serves as a key precursor in the research and production of protease inhibitors, a significant class of drugs.
• Agrochemical Synthesis: Used in the research and development of advanced agrochemicals, such as herbicides and pesticides, leveraging the stability of the CF3 group.
• Material Science Research: Employed in the development of specialty chemicals and advanced materials, including liquid crystals and polymers.
• Chemical Biology & Medicinal Chemistry: Acts as a versatile scaffold for constructing compound libraries used in high-throughput screening and hit-to-lead optimization.

Basic Information

Product Name	3-Trifluoromethyl-Benzamidine Hcl
CAS No.	62980-03-4
Molecular Formula	C8H8ClF3N2
Molecular Weight	224.61 g/mol
Synonyms	3-(Trifluoromethyl)benzamidine hydrochloride; m-Trifluoromethylbenzamidine HCl; Benzenecarboximidamide, 3-(trifluoromethyl)-, hydrochloride; 3-Trifluoromethylbenzenecarboximidamide hydrochloride; 3-Carbamimidoylbenzotrifluoride hydrochloride; α,α,α-Trifluoro-m-toluamidine hydrochloride; 3-(Trifluoromethyl)benzenecarboximidamide monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethyl-Benzamidine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.