Description

(2S,3S)-3',4'-Dihydro-3α,5,7-Trihydroxy-5'-Methoxy-2',2'-Dimethyl-2,6'-Bi[2H-1-Benzopyran]-4(3H)-One is a high-purity, complex flavonoid derivative belonging to the class of biflavonoids. This compound is valued for its specific stereochemistry and structural complexity, making it a critical reference standard and intermediate for advanced research and development. It is primarily sought by the pharmaceutical, nutraceutical, and fine chemical industries for applications in analytical method development, bioactivity studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of related active pharmaceutical ingredients (APIs) and natural product extracts.
• Biochemical Research: Serves as a key intermediate or probe in studying enzyme inhibition, antioxidant mechanisms, and other structure-activity relationship (SAR) studies.
• Nutraceutical Development: Employed in the formulation and standardization of high-value botanical extracts and dietary supplements targeting specific health benefits.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the synthesis of novel chemical entities and complex natural product analogs.
• Analytical Chemistry: Utilized in the development and validation of chromatographic methods (HPLC, LC-MS) for the quantification of flavonoids in complex matrices.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations due to its polyphenolic structure.

Basic Information

Product Name	(2S,3S)-3',4'-Dihydro-3α,5,7-Trihydroxy-5'-Methoxy-2',2'-Dimethyl-2,6'-Bi[2H-1-Benzopyran]-4(3H)-One
CAS No.	62499-03-0
Molecular Formula	C31H28O9
Molecular Weight	544.55 g/mol
Synonyms	GB-1a; (2S,3S)-GB-1a; Garcinia biflavonoid 1a; 3′,4′-Dihydro-3α,5,7-trihydroxy-5′-methoxy-2′,2′-dimethyl-2,6′-bi[2H-1-benzopyran]-4(3H)-one; (2S,3S)-3',4'-Dihydro-3α,5,7-trihydroxy-5'-methoxy-2',2'-dimethyl-2,6'-bichromone-4(3H)-one; Biflavonoid GB-1a; Garcinia Biflavonoid
EINECS	Contact for details

Quality Control

Our (2S,3S)-3',4'-Dihydro-3α,5,7-Trihydroxy-5'-Methoxy-2',2'-Dimethyl-2,6'-Bi[2H-1-Benzopyran]-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, MS). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (2S,3S)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.