Description

Apigenin-7-o-Glucuronide-6'-Ethyl Ester is a specific, semi-synthetic derivative of the flavonoid apigenin, modified with a glucuronide moiety and an ethyl ester group. This targeted molecular structure is valued for its enhanced stability and bioavailability compared to its parent compound, making it a crucial reference standard and intermediate in advanced research. It is primarily required by pharmaceutical R&D, nutraceutical development, and analytical laboratories focused on flavonoid metabolism and pharmacokinetic studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of apigenin metabolites in drug development and bioanalytical studies.
• Metabolite Research: Serves as a critical standard for identifying and studying the glucuronidated metabolites of apigenin in in vitro and in vivo models.
• Bioavailability Enhancement Studies: Investigated as a prodrug or modified compound to improve the solubility and absorption profile of apigenin.
• Enzyme Inhibition Assays: Utilized in biochemical research to study interactions with enzymes like UDP-glucuronosyltransferases (UGTs).
• Nutraceutical Ingredient Development: Explored as a potential active ingredient in advanced dietary supplements due to its modified properties.
• Academic Research: Employed in universities and research institutes for studies on flavonoid chemistry, modification, and biological activity.

Basic Information

Product Name	Apigenin-7-o-Glucuronide-6'-Ethyl Ester
CAS No.	62268-42-2
Molecular Formula	C23H22O11
Molecular Weight	474.41 g/mol
Synonyms	Apigenin 7-O-β-D-glucuronide 6'-ethyl ester; 6'-O-Ethylapigenin-7-O-β-D-glucuronide; Apigenin-7-O-β-D-glucopyranuronoside, 6'-ethyl ester; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 7-(6'-O-ethyl-β-D-glucopyranuronoside); 4',5,7-Trihydroxyflavone-7-O-β-D-glucuronide-6'-ethyl ester
EINECS	Contact for details

Quality Control

Our Apigenin-7-o-Glucuronide-6'-Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.