Description

(E)-1-(Trimethylsilyl)-3-Pentene-1-Yne is a specialized organosilicon building block featuring a conjugated enyne system protected by a trimethylsilyl group. This unique structure makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications requiring precise carbon-silicon bond formation and subsequent functionalization.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds requiring conjugated systems or silicon-containing moieties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the enyne functionality can be leveraged for biological activity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers and silicon-based functional materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Sonogashira, Heck) and cycloadditions to construct complex organic molecules for academic and industrial research.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic complexes used in homogeneous catalysis.

Basic Information

Product Name	(E)-1-(Trimethylsilyl)-3-Pentene-1-Yne
CAS No.	62170-41-6
Molecular Formula	C8H14Si
Molecular Weight	138.28 g/mol
Synonyms	(E)-3-Trimethylsilyl-1-penten-4-yne; 1-Penten-4-yne, 3-(trimethylsilyl)-, (E)-; 3-(Trimethylsilyl)-1-penten-4-yne, (E)-; (E)-3-(Trimethylsilyl)penta-1-en-4-yne; TMS-enyne; Trimethyl((1E)-1-penten-4-yn-1-yl)silane
EINECS	Contact for details

Quality Control

Our (E)-1-(Trimethylsilyl)-3-Pentene-1-Yne is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.