Description

1-[[(2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2α,4Aα-Methanonaphthalen]-8-Yl]Ethanone is a high-purity, optically active synthetic intermediate characterized by its complex, rigid polycyclic structure. This compound matters as a versatile chiral building block for the synthesis of advanced molecules, offering precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for creating novel active ingredients and fragrances.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Fragrance & Flavor Synthesis: Used in the development of complex, woody, and amber-like fragrance molecules due to its methanonaphthalene backbone.
• Agrochemical Research: Acts as a scaffold for creating new, stereospecific pesticides and herbicides with potentially enhanced activity.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Asymmetric Catalysis: Employed as a ligand or a substrate in the development and testing of new asymmetric catalytic processes.
• Academic & Industrial R&D: Utilized in organic chemistry research for methodology development and the study of structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	1-[[(2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2α,4Aα-Methanonaphthalen]-8-Yl]Ethanone
CAS No.	62075-20-1
Molecular Formula	C17H26O
Molecular Weight	246.39 g/mol
Synonyms	(2S)-8-Acetyl-1,1,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene; (-)-Ambrox; (8S)-8-Acetyl-1,1,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene; (S)-(-)-Ambroxide Precursor; 1-[(2S)-1,1,5,5-Tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalen-8-yl]ethanone; Chiral Ambrox Intermediate; (S)-8-Acetyl-1,1,5,5-tetramethyloctahydro-2,4a-methanonaphthalene
EINECS	Contact for details

Quality Control

Our 1-[[(2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2α,4Aα-Methanonaphthalen]-8-Yl]Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (S-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.