Description

4-(Tetrahydro-Pyran-4-Yl)-Phenylamine is a versatile aromatic amine derivative featuring a tetrahydropyran moiety, which imparts unique steric and electronic properties. This compound serves as a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Monomer or precursor for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Versatile starting material for academic and industrial research in medicinal chemistry and synthetic methodology development.
• Dye and Pigment Industry: Intermediate for the synthesis of advanced colorants and functional dyes.

Basic Information

Product Name	4-(Tetrahydro-Pyran-4-Yl)-Phenylamine
CAS No.	62071-40-3
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	4-(4-Aminophenyl)tetrahydro-2H-pyran; 4-(Tetrahydro-2H-pyran-4-yl)aniline; 4-Aminophenyl tetrahydropyran-4-yl ketone (related); 4-(Oxan-4-yl)aniline; 4-(Tetrahydro-2H-pyran-4-yl)benzenamine; 4-Pyran-4-yl-phenylamine; 62071-40-3; 4-(4-Pyranyl)aniline
EINECS	Contact for details

Quality Control

Our 4-(Tetrahydro-Pyran-4-Yl)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.