Description

1-tert-Butyl-4-Chlorocyclohexane is a versatile halogenated cycloalkane derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bulky tert-butyl group and a reactive chlorine substituent, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the tert-butyl group can impart favorable metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and functional additives for specialty polymers, influencing properties like thermal stability and solubility.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution and elimination reactions to introduce the tert-butylcyclohexyl moiety into more complex molecules.
• Fragrance & Flavor Chemistry: Acts as an intermediate for synthesizing specific musky or woody aroma chemicals, leveraging the stability of the cyclohexane backbone.

Basic Information

Product Name	1-tert-Butyl-4-Chlorocyclohexane
CAS No.	62056-46-6
Molecular Formula	C10H19Cl
Molecular Weight	174.71 g/mol
Synonyms	4-Chloro-1-tert-butylcyclohexane; 1-(1,1-Dimethylethyl)-4-chlorocyclohexane; 4-tert-Butylchlorocyclohexane; p-tert-Butylchlorocyclohexane; trans-1-tert-Butyl-4-chlorocyclohexane (possible isomer); cis-1-tert-Butyl-4-chlorocyclohexane (possible isomer); tert-Butyl-4-chlorocyclohexane; NSC 169102
EINECS	Contact for details

Quality Control

Every batch of 1-tert-Butyl-4-Chlorocyclohexane is manufactured under strict quality management protocols. We employ advanced analytical techniques including GC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, isomer content, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from strong bases and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed at temperatures between 15-25°C to prevent evaporation and concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Isomer Ratio (cis/trans)	Reported on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.