Description

3β,4α,5β,6α-Tetrahydroxytetrahydro-2H-Pyran-2α-Carboxamide is a high-purity, specialized carbohydrate derivative with a defined stereochemical configuration. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise molecular architecture for complex chemical transformations. It is essential for research and development in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), glycosidase inhibitors, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including antiviral and anticancer drugs.
• Glycoscience Research: Used as a precursor or mimic in the study of carbohydrate-processing enzymes (glycosidases and glycosyltransferases).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, stereochemically defined natural products and specialty chemicals.
• Bioconjugate Chemistry: Serves as a functionalized sugar moiety for linking to proteins, peptides, or other biomolecules in drug delivery system development.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological development in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	3β,4α,5β,6α-Tetrahydroxytetrahydro-2H-Pyran-2α-Carboxamide
CAS No.	61914-43-0
Molecular Formula	C7H13NO6
Molecular Weight	207.18 g/mol
Synonyms	2-Carbamoyl-2-deoxy-D-gluconic acid δ-lactone; 2-Deoxy-2-carbamoyl-D-glucono-1,5-lactone; D-Gluconamide, 2-deoxy-, 1,5-lactone; (2R,3S,4R,5R)-3,4,5,6-Tetrahydroxy-2-(hydroxymethyl)piperidine-2-carboxamide (tautomeric form); Tetrahydroxypiperidinecarboxamide; Gluconamide lactone derivative
EINECS	Contact for details

Quality Control

Every batch of 3β,4α,5β,6α-Tetrahydroxytetrahydro-2H-Pyran-2α-Carboxamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.