Description

1,3-Dibromo-4-Methoxy-2-Methyl-5-Nitrobenzene is a high-purity, multi-functional halogenated aromatic compound used as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the nitro and bromo groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard for analytical method development in organic chemistry.

Basic Information

Product Name	1,3-Dibromo-4-Methoxy-2-Methyl-5-Nitrobenzene
CAS No.	61827-59-6
Molecular Formula	C8H7Br2NO3
Molecular Weight	324.96 g/mol
Synonyms	2,4-Dibromo-5-Methoxy-6-Nitrotoluene; 5-Methoxy-2,4-dibromo-6-nitrotoluene; 1,3-Dibromo-4-methoxy-2-methyl-5-nitro-benzene; Benzene, 1,3-dibromo-4-methoxy-2-methyl-5-nitro-; 4-Methoxy-2-methyl-5-nitro-1,3-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-4-Methoxy-2-Methyl-5-Nitrobenzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing all specification parameters, including assay by HPLC and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.