Description

(2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalene-8-Carbaldehyde is a high-purity, chiral aldehyde derivative of a complex methanonaphthalene structure, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its defined stereochemistry and functional group, which enable the precise construction of complex molecular architectures for high-value applications. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries, where it is used to synthesize novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides, where the specific (2S) configuration can be crucial for biological activity.
• Fragrance and Flavor Chemistry: Serves as a precursor for synthesizing complex, woody, and amber-like odorants in high-end perfumery and flavor compounds.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique optical or mechanical properties.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to create novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Academic and Industrial R&D: A valuable reference standard and starting material for methodological studies in organic chemistry and total synthesis projects.

Basic Information

Item	Details
Product Name	(2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalene-8-Carbaldehyde
CAS No.	61826-54-8
Molecular Formula	C16H24O
Molecular Weight	232.36 g/mol
Synonyms	(2S)-8-Formyl-1,1,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene; (S)-(-)-8-Formyl-1,1,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene; (S)-8-Aldehyde-1,1,5,5-tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene; (2S)-1,1,5,5-Tetramethyl-1,2,3,4,5,6,7,8-octahydro-2,4a-methanonaphthalene-8-carboxaldehyde; Chiral Methanonaphthalene Aldehyde
EINECS	Contact for details

Quality Control

Our (2S)-1,3,4,5,6,7-Hexahydro-1,1,5,5-Tetramethyl-2H-2,4A-Methanonaphthalene-8-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (2S)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.