Description

(+)-(18-Crown-6)-2,3,11,12-Tetracarboxylic Acid is a highly functionalized, chiral crown ether derivative that serves as a powerful and selective complexing agent. Its value lies in its ability to bind specific cations with high affinity, making it an indispensable tool for chiral recognition, phase-transfer catalysis, and molecular sensing. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing enantioselective syntheses and separation protocols.

Application

• Chiral Phase-Transfer Catalyst: Enables enantioselective alkylation and other C-C bond-forming reactions in asymmetric synthesis.
• Molecular Recognition & Sensing: Acts as a key component in the design of chiral sensors and selective electrodes for ion detection.
• Enantiomer Separation: Used as a chiral selector or additive in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for resolving racemic mixtures.
• Supramolecular Chemistry Building Block: Serves as a precursor for constructing more complex, functionalized host molecules and molecular machines.
• Metal Ion Extraction & Transport: Facilitates the selective extraction or membrane transport of specific alkali and alkaline earth metal ions.
• Polymer Modification: Incorporated into polymers to create materials with ion-selective properties for specialized filtration or sensing applications.

Basic Information

Product Name	(+)-(18-Crown-6)-2,3,11,12-Tetracarboxylic Acid
CAS No.	61696-54-6
Molecular Formula	C20H24O14
Molecular Weight	488.40 g/mol
Synonyms	(18-Crown-6)-2,3,11,12-tetracarboxylic acid, (R)-(+)-form; (R)-(+)-18-Crown-6-tetracarboxylic acid; (+)-18-Crown-6-tetracarboxylic acid; (R)-18-Crown-6-2,3,11,12-tetracarboxylic acid; (2R,3R,11R,12R)-2,3,11,12-Tetrakis(carboxymethyl)-18-crown-6; Chiral 18-crown-6 tetracarboxylic acid; Dicyclohexano-18-crown-6-tetracarboxylic acid (chiral derivative)
EINECS	Contact for details

Quality Control

Our (+)-(18-Crown-6)-2,3,11,12-Tetracarboxylic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm enantiomeric excess and identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and key physical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.