Description

Ethyl 2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Acetate is a versatile protected glycolic acid derivative, serving as a crucial synthetic intermediate in advanced organic synthesis. Its primary value lies in the THP-protected hydroxyl group, which provides excellent stability under a wide range of reaction conditions while allowing for selective deprotection. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected glycolic acid equivalent for the introduction of hydroxyacetic acid moieties into peptide chains.
• Polymer Chemistry: Monomer or co-monomer for creating specialty polymers with tailored properties, such as biodegradable polyesters.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Used in the research and development of novel organic materials and liquid crystals.
• Flavor and Fragrance Industry: Intermediate for the synthesis of certain ester-based aroma chemicals.
• Academic and R&D: Valuable reagent for methodological development and exploratory organic synthesis in research laboratories.

Basic Information

Product Name	Ethyl 2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Acetate
CAS No.	61675-94-3
Molecular Formula	C9H16O4
Molecular Weight	188.22 g/mol
Synonyms	Ethyl (Tetrahydro-2H-pyran-2-yloxy)acetate; Ethyl 2-(Tetrahydro-2H-pyran-2-yloxy)acetate; 2-(Tetrahydro-2H-pyran-2-yloxy)acetic Acid Ethyl Ester; THP-protected Ethyl Glycolate; Ethyl O-(Tetrahydro-2-pyranyl)glycolate; Glycolic Acid Ethyl Ester 2-Tetrahydropyranyl Ether; Acetic acid, 2-((tetrahydro-2H-pyran-2-yl)oxy)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-((Tetrahydro-2H-Pyran-2-Yl)Oxy)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed batch-specific results are provided and can be tailored to meet specific customer requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.440 - 1.450
Density (g/mL at 20°C)	1.08 - 1.12

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.