Description

Cyclopentaneheptanoic Acid, 5-(Acetyloxy)-2-(Hydroxymethyl)-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Methyl Ester, (1R,2S,3R,5S)- is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a crucial building block in the synthesis of prostaglandin analogs and other bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Prostaglandin Analog Research: Serves as a core structural precursor for developing new analogs targeting ocular hypertension, gastrointestinal disorders, and cardiovascular conditions.
• Process Chemistry & Scale-Up: Used in process optimization and pilot-scale manufacturing of complex target molecules under current Good Manufacturing Practice (cGMP) conditions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical entities and biological pathways.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API production.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value compounds.

Basic Information

Product Name	Cyclopentaneheptanoic Acid, 5-(Acetyloxy)-2-(Hydroxymethyl)-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Methyl Ester, (1R,2S,3R,5S)-
CAS No.	61302-47-4
Molecular Formula	C21H34O7
Molecular Weight	398.49 g/mol
Synonyms	(1R,2S,3R,5S)-Methyl 5-(Acetyloxy)-2-(Hydroxymethyl)-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]cyclopentaneheptanoate; Methyl (1R,2S,3R,5S)-5-(Acetyloxy)-2-(Hydroxymethyl)-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]cyclopentaneheptanoate; Latanoprost Intermediate; Prostaglandin F2α Analog Intermediate; THP-Protected Prostaglandin Intermediate; 9α,11α,15S-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5Z,13E-dien-1-oic Acid Methyl Ester Derivative; 5-Acetoxy-2-Hydroxymethyl-3-(Tetrahydro-2H-Pyran-2-Yloxy)cyclopentaneheptanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Cyclopentaneheptanoic Acid, 5-(Acetyloxy)-2-(Hydroxymethyl)-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, Methyl Ester, (1R,2S,3R,5S)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.