Description

(5S)-5-Acetyltetrahydrofuran-2-One is a high-purity chiral lactone derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for constructing complex molecules with specific spatial orientations. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and neurological therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where stereoselectivity is crucial for bioactivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, fragrances, and performance materials requiring high stereochemical purity.
• Asymmetric Catalysis Research: Serves as a starting material or ligand precursor in the development of new chiral catalysts and methodologies.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities and corporate R&D labs exploring new reaction pathways and molecular architectures.

Basic Information

Product Name	(5S)-5-Acetyltetrahydrofuran-2-One
CAS No.	61262-92-8
Molecular Formula	C6H8O3
Molecular Weight	128.13 g/mol
Synonyms	(5S)-5-Acetyloxolan-2-one; (S)-5-Acetyltetrahydro-2-furanone; (S)-γ-Acetyl-γ-butyrolactone; (S)-5-Acetyl-2-oxotetrahydrofuran; (S)-5-Acetyldihydrofuran-2(3H)-one; (5S)-5-Acetyloxolan-2-one; (S)-5-Acetyl-2-oxotetrahydrofuran
EINECS	Contact for details

Quality Control

Our (5S)-5-Acetyltetrahydrofuran-2-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.