Description

17-o-tert-Butyldimethylsilyl 5,14-Androstadiene-3β,17β-Diol CAS NO 61252-32-2 is a high-purity, protected steroid derivative used as a critical synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of complex steroid-based molecules, enabling precise chemical modifications. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Hormone Analog Synthesis: Serves as a precursor in the creation of modified androgen and estrogen analogs for biological evaluation.
• Chemical Reference Standard: Employed as a high-purity analytical standard for method development and quality control in laboratories.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Biochemical Research: Applied in studies investigating steroid receptor interactions and metabolic pathways.

Basic Information

Product Name	17-o-tert-Butyldimethylsilyl 5,14-Androstadiene-3β,17β-Diol
CAS No.	61252-32-2
Molecular Formula	C25H42O2Si
Molecular Weight	402.69 g/mol
Synonyms	5,14-Androstadiene-3β,17β-diol 17-tert-butyldimethylsilyl ether; 17β-[(tert-Butyldimethylsilyl)oxy]-5,14-androstadiene-3β-ol; 3β-Hydroxy-17β-[(tert-butyldimethylsilyl)oxy]-5,14-androstadiene; TBDMS-protected 5,14-Androstadienediol
EINECS	Contact for details

Quality Control

Our 17-o-tert-Butyldimethylsilyl 5,14-Androstadiene-3β,17β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.