Description

(S)-3,4-Dihydro-4-Phenyl-2H-1-Benzopyran-2-One CAS NO 61198-52-5 is a high-purity chiral intermediate belonging to the class of benzopyranones. This compound is of significant commercial importance as a key building block in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of enantioselective drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Precursor: Serves as a ligand precursor or a core structure in the development of chiral catalysts for stereoselective synthesis.
• Agrochemical Research: Used in the development of novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical purity.
• Material Science: Investigated as a monomer or additive for creating chiral polymers and liquid crystalline materials with specific optical properties.

Basic Information

Product Name	(S)-3,4-Dihydro-4-Phenyl-2H-1-Benzopyran-2-One
CAS No.	61198-52-5
Molecular Formula	C15H12O2
Molecular Weight	224.26 g/mol
Synonyms	(S)-4-Phenylchroman-2-one; (S)-4-Phenyl-3,4-dihydro-2H-1-benzopyran-2-one; (S)-4-Phenylcoumaran-2-one; (S)-Flavan-2-one; (S)-2-Chromanone, 4-phenyl-; (S)-4-Phenyl-2-chromanone; (S)-3,4-Dihydro-4-phenylcoumarin; (S)-4-Phenyldihydrocoumarin
EINECS	Contact for details

Quality Control

Our (S)-3,4-Dihydro-4-Phenyl-2H-1-Benzopyran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.