Description

α-Cyanocinnamic Acid is a specialized cinnamic acid derivative featuring a cyano group at the alpha position, which significantly enhances its reactivity as a Michael acceptor and a versatile synthetic building block. This compound is valued for its role in facilitating carbon-carbon bond formation and serving as a key precursor in heterocyclic chemistry. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of protease inhibitors, kinase inhibitors, and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Serves as a key reactant for producing dyes, pigments, and advanced organic materials.
• Academic & Industrial Research: Employed in methodological studies, catalysis research, and as a standard in analytical chemistry.
• Peptide Mimetics: The cyano and carboxylic acid functionalities make it useful for constructing non-peptidic scaffolds that mimic peptide structures.

Basic Information

Product Name	α-Cyanocinnamic Acid
CAS No.	61147-65-7
Molecular Formula	C10H7NO2
Molecular Weight	173.17 g/mol
Synonyms	2-Cyano-3-phenylpropenoic Acid; (E)-2-Cyano-3-phenylacrylic Acid; trans-α-Cyanocinnamic Acid; α-Cyano-β-phenylacrylic Acid; 3-Phenyl-2-cyanoacrylic Acid; (2E)-2-Cyano-3-phenyl-2-propenoic Acid; Cinnamic acid, α-cyano-; CCRIS 5361
EINECS	262-622-6

Quality Control

Our α-Cyanocinnamic Acid is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or kept in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	195°C - 205°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.