Description

Cyanomethyl-2-Acetamido-2-Deoxy-3-4-6-Tri-o-Acetyl-1-Thio-B-D- Glucopyranoside CAS NO 61145-37-7 is a key thioglycoside building block and advanced intermediate in synthetic organic chemistry. This compound is valued for its role in the efficient synthesis of complex oligosaccharides and glycoconjugates, which are critical in pharmaceutical and biochemical research. It is primarily sought by research institutions and manufacturers developing novel therapeutics, diagnostic agents, and tools for glycobiology studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel glycosidase inhibitors and other carbohydrate-based therapeutic agents.
• Glycoconjugate Synthesis: Used as a glycosyl donor for the construction of S-linked oligosaccharides and neoglycoconjugates for biological studies.
• Chemical Biology Probes: Serves as a building block for creating labeled sugar analogs and activity-based probes to study enzymatic pathways.
• Carbohydrate Chemistry Research: An essential reagent for academic and industrial research focused on developing new glycosylation methodologies.
• Bioconjugation: Facilitates the site-specific attachment of carbohydrate motifs to proteins, peptides, or surfaces for vaccine and diagnostic development.

Basic Information

Product Name	Cyanomethyl-2-Acetamido-2-Deoxy-3-4-6-Tri-o-Acetyl-1-Thio-B-D- Glucopyranoside
CAS No.	61145-37-7
Molecular Formula	C₁₆H₂₂N₂O₈S
Molecular Weight	402.42 g/mol
Synonyms	2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranose cyanomethyl glycoside; 1-Thio-β-D-glucopyranoside, 2-(acetylamino)-1,2-dideoxy-, 3,4,6-triacetate, cyanomethyl; Cyanomethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside; Cyanomethyl 2-deoxy-2-acetamido-3,4,6-tri-O-acetyl-1-thio-β-D-glucopyranoside; Thioglycoside donor; Ac₃GlcNAcβ-SCH₂CN
EINECS	Contact for details

Quality Control

Our Cyanomethyl-2-Acetamido-2-Deoxy-3-4-6-Tri-o-Acetyl-1-Thio-B-D- Glucopyranoside is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and synthesis. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.