Description

1-(1,1-Dimethylethyl)-5,6,7,8-Tetrahydro-2-Naphthol is a substituted tetralin derivative, specifically a hindered phenolic compound with a tertiary butyl group. This structure is significant as it provides steric hindrance, making it a valuable intermediate and building block in the synthesis of more complex molecules, particularly in the pharmaceutical and specialty chemical sectors. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional additives.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antioxidant properties.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the hindered phenol moiety can contribute to stability and activity.
• Polymer Additive Precursor: Serves as a starting material for manufacturing specialized antioxidants and light stabilizers for plastics and elastomers.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create complex ligands for catalytic applications.
• Fine Chemical Synthesis: Intermediate for producing dyes, pigments, and other high-value specialty chemicals.
• Research & Development: A versatile scaffold for medicinal chemistry and chemical biology research programs.

Basic Information

Item	Detail
Product Name	1-(1,1-Dimethylethyl)-5,6,7,8-Tetrahydro-2-Naphthol
CAS No.	60834-65-3
Molecular Formula	C₁₄H₂₀O
Molecular Weight	204.31 g/mol
Synonyms	2-tert-Butyl-5,6,7,8-tetrahydro-2-naphthol; 2-(tert-Butyl)-5,6,7,8-tetrahydronaphthalen-2-ol; 5,6,7,8-Tetrahydro-2-tert-butylnaphthol; 2-tert-Butyl-1,2,3,4-tetrahydronaphthalen-6-ol; 6-tert-Butyl-1,2,3,4-tetrahydronaphthalen-2-ol; tert-Butyl tetralin phenol; TBTHN
EINECS	Contact for details

Quality Control

Our 1-(1,1-Dimethylethyl)-5,6,7,8-Tetrahydro-2-Naphthol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.