Description

m-Peg3-Ms CAS NO 60696-83-5 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a methanesulfonate (mesylate, Ms) group at one terminus and a methoxy group at the other. This compound is a critical reagent in bioconjugation and pharmaceutical development, enabling the controlled attachment of molecules through nucleophilic substitution reactions. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, proteomics, and advanced material science to create stable, functionalized conjugates for drug delivery systems and diagnostic tools.

Application

• Bioconjugation Reagent: Used to attach drugs, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles via the reactive mesylate group.
• ADC (Antibody-Drug Conjugate) Development: Serves as a key linker component for constructing stable, cleavable, or non-cleavable ADCs.
• PEGylation Chemistry: Acts as a functionalized PEG spacer to improve the solubility, stability, and pharmacokinetic properties of therapeutic biomolecules.
• Crosslinking Agent: Employed in the synthesis of hydrogels, polymer networks, and surface modifications for biomaterials.
• Small Molecule Prodrug Synthesis: Facilitates the creation of prodrugs by linking active pharmaceutical ingredients to promoieties for controlled release.
• Diagnostic Probe Construction: Used in the development of imaging agents and biosensors by conjugating targeting ligands with reporter molecules.

Basic Information

Product Name	m-Peg3-Ms
CAS No.	60696-83-5
Molecular Formula	C9H20O6S
Molecular Weight	256.32 g/mol
Synonyms	mPEG3-Ms; Methoxy-PEG3-mesylate; 1-(Methoxytriethyleneoxy)-2-methanesulfonyloxyethane; 2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate; mPEG3-OMs; Triethylene glycol monomethyl ether mesylate; PEG3 methyl ether mesylate; m-PEG3-mesylate
EINECS	Contact for details

Quality Control

Our m-Peg3-Ms is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.