Description

S-2-Bromo-2-Phenylacetic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for introducing the α-bromo phenylacetic acid moiety, a key structural feature for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise chiral precursors for API development, ligand synthesis, and specialty chemical production.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Asymmetric Synthesis: Serves as a versatile starting material or reagent in stereoselective reactions, including nucleophilic substitutions and coupling reactions, to construct enantiomerically pure compounds.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for optimal activity.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands for transition metal catalysis, enabling highly enantioselective transformations in fine chemical manufacturing.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for studying reaction mechanisms involving α-halo acids.
• Specialty & Fine Chemicals: Used in the custom synthesis of complex, high-value molecules for electronics, perfumery, and advanced material applications.

Basic Information

Product Name	S-2-Bromo-2-Phenylacetic Acid
CAS No.	60686-78-4
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	(S)-2-Bromo-2-phenylacetic acid; (S)-α-Bromophenylacetic acid; (S)-O-Bromomandelic acid; (S)-Bromophenylacetic acid; L-2-Bromo-2-phenylacetic acid; (S)-Bromobenzeneacetic acid; (2S)-2-Bromo-2-phenylacetic acid; (S)-(-)-2-Bromo-2-phenylacetic acid
EINECS	Contact for details

Quality Control

Our S-2-Bromo-2-Phenylacetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR, and quantification of key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.