Description

2,2-Dimethyltetrahydro-2H-Pyran-4-Carbonitrile (Saltdata: Free) is a versatile heterocyclic nitrile building block with significant synthetic utility. Its unique structure, featuring a protected pyran ring, makes it a valuable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on novel active ingredients. The CAS number for this substance is 60549-63-5.

Application

This specialized chemical intermediate enables a range of advanced synthetic transformations across high-value industries.

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new pesticides, herbicides, and fungicides with enhanced efficacy and environmental profiles.
• Fine Chemical Production: Used in the manufacture of complex, high-purity specialty chemicals for electronics, catalysis, and material science.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and medicinal chemistry programs.
• Ligand and Catalyst Development: The nitrile and ether functionalities can be modified to create novel ligands for asymmetric catalysis and metal complexes.

Basic Information

Product Name	2,2-Dimethyltetrahydro-2H-Pyran-4-Carbonitrile (Saltdata: Free)
CAS No.	60549-63-5
Molecular Formula	C8H13NO
Molecular Weight	139.19 g/mol
Synonyms	4-Cyano-2,2-dimethyltetrahydropyran; 2,2-Dimethyl-4-cyanotetrahydropyran; 2,2-Dimethyltetrahydro-2H-pyran-4-carbonitrile; Tetrahydro-2,2-dimethyl-4-pyrancarbonitrile; 4-Pyrancarbonitrile, tetrahydro-2,2-dimethyl-; 60549-63-5 (CAS)
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyltetrahydro-2H-Pyran-4-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for use in regulated pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.