Description

3-Methyl-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-2-Butanone is a valuable protected ketone derivative, serving as a versatile synthon in advanced organic synthesis. Its core value lies in the THP-protected hydroxyl group adjacent to the ketone, which provides orthogonal reactivity and stability for multi-step synthetic sequences. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for constructing complex molecular architectures like active pharmaceutical ingredients (APIs) and natural product analogs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the preparation of chiral synthons for the production of enantiomerically pure compounds.
• Natural Product Synthesis: Serves as a precursor in the total synthesis of complex natural products and their analogs.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in specialty polymer formulations.
• Agrochemical Research: Employed in the development and synthesis of novel agrochemicals and plant protection agents.
• Material Science: Utilized in the research and development of advanced organic materials and liquid crystals.

Basic Information

Product Name	3-Methyl-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-2-Butanone
CAS No.	60283-66-1
Molecular Formula	C10H18O3
Molecular Weight	186.25 g/mol
Synonyms	3-Methyl-3-(tetrahydro-2H-pyran-2-yloxy)butan-2-one; 2-Butanone, 3-methyl-3-[(tetrahydro-2H-pyran-2-yl)oxy]-; 3-Methyl-3-(tetrahydropyran-2-yloxy)butan-2-one; THP-protected 3-hydroxy-3-methyl-2-butanone; 3-Hydroxy-3-methyl-2-butanone THP ether; 3-Methyl-3-(2-tetrahydropyranyloxy)-2-butanone
EINECS	Contact for details

Quality Control

Our 3-Methyl-3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-2-Butanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.