Description

5-Hydroxymebendazole is a key pharmaceutical intermediate and metabolite of the anthelmintic drug Mebendazole. This compound matters for its critical role in drug metabolism studies, analytical reference standard preparation, and the synthesis of advanced therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs) for veterinary and human use.

Application

• Primary reference standard for the HPLC and LC-MS analysis of Mebendazole and its metabolites in biological matrices.
• Critical intermediate in the synthesis and process development of novel anthelmintic compounds.
• Metabolite for pharmacokinetic and drug metabolism studies to understand the efficacy and safety profile of benzimidazole-class drugs.
• Raw material for the preparation of certified analytical standards and impurity markers in pharmaceutical quality control.
• Research chemical in parasitology and veterinary medicine for developing new treatment protocols.
• Building block in organic synthesis for modifying the benzimidazole scaffold to explore new biological activities.

Basic Information

Product Name	5-Hydroxymebendazole
CAS No.	60254-95-7
Molecular Formula	C₁₆H₁₃N₃O₃
Molecular Weight	295.29 g/mol
Synonyms	5-Hydroxy Mebendazole; Mebendazole Metabolite; Mebendazole Hydroxy Metabolite; 5-(Benzoylamino)-2-(hydroxymethyl)-1H-benzimidazol-6-ol; 5-Benzoylamino-6-hydroxy-2-benzimidazolecarbamic acid methyl ester; 5-Benzoylamino-2-hydroxymethyl-6-benzimidazole carbamate; MBZ-OH; Mebendazole-5-hydroxy
EINECS	Contact for details

Quality Control

Our 5-Hydroxymebendazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.