Description

Glabrone is a naturally occurring isoflavone compound, a key bioactive constituent found in the roots of licorice (Glycyrrhiza glabra). This compound is valued for its significant role in biochemical research and development due to its distinct structural and biological properties. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries, where precise chemical identity and purity are paramount for product efficacy and safety.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quality control and quantification of licorice extracts and related products in pharmacopoeial testing.
• Biochemical Research: Serves as a key intermediate or probe in studies investigating enzyme inhibition, anti-inflammatory pathways, and other cellular mechanisms.
• Nutraceutical Development: Employed as a marker compound for the standardization of herbal supplements and functional foods derived from Glycyrrhiza species to ensure consistent potency.
• Cosmetic Ingredient Research: Investigated for potential skin-benefiting properties in the development of advanced cosmetic and dermatological formulations.
• Analytical Chemistry: Essential for method development and validation in chromatographic techniques (HPLC, LC-MS) for the accurate analysis of complex botanical matrices.

Basic Information

Product Name	Glabrone
CAS No.	60008-02-8
Molecular Formula	C₂₀H₁₈O₄
Molecular Weight	322.35 g/mol
Synonyms	7-Hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 3-(4-Hydroxyphenyl)-7-hydroxy-6-methoxy-4H-chromen-4-one; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (tautomeric form); Licorice isoflavone; Glycyrrhiza glabra isoflavone
EINECS	Contact for details

Quality Control

Every batch of our Glabrone is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for research and industrial applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and MS analyses, is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.