Description

N,N’-S-Trimethylisothiouronium Iodide is a versatile organosulfur compound with a quaternary ammonium structure, serving as a key reagent and intermediate in advanced chemical synthesis. Its primary commercial value lies in its role as a highly effective methylation and thiomethylation agent, offering superior reactivity and selectivity for demanding transformations. This product is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular modification is critical.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide derivatives and other sulfur-containing drug molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the introduction of methylthio or dimethylamino groups.
• Organic Synthesis Reagent: Acts as a potent methylating and thiomethylating agent in nucleophilic substitution reactions, valuable for creating complex organic structures in fine chemical manufacturing.
• Bioconjugation Chemistry: Employed in biochemical research for modifying proteins, peptides, and other biomolecules, facilitating the study of structure-activity relationships.
• Polymer Modification: Utilized to introduce functional groups into polymer chains, altering material properties such as solubility, adhesion, and reactivity for advanced material science applications.
• Catalyst and Ligand Precursor: Serves as a starting material for generating ligands used in transition metal catalysis for asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	N,N’-S-Trimethylisothiouronium Iodide
CAS No.	6972-04-9
Molecular Formula	C4H11IN2S
Molecular Weight	246.11 g/mol
Synonyms	Trimethylisothiouronium Iodide; S-Methyl-N,N-dimethylisothiouronium Iodide; 1,1,3-Trimethyl-2-thiopseudourea Iodide; Isothiouronium, N,N,S-trimethyl-, iodide; TMTU Iodide; NSC 403697; AI3-52244; CCRIS 6681
EINECS	230-219-3

Quality Control

Our N,N’-S-Trimethylisothiouronium Iodide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	178°C - 182°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.