Description

2-(5-Bromo-2,4-Dimethoxy-Phenyl)Chromen-4-One is a specialized brominated chromenone derivative, a key intermediate in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is integral to the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential therapeutic agents and for use as a reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for method development, validation, and quality control in HPLC, LC-MS, and NMR analysis.
• Chemical Biology Probe: Employed in biochemical assays to study protein-ligand interactions and cellular mechanisms.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create complex heterocyclic compounds for material science and agrochemical research.

Basic Information

Product Name	2-(5-Bromo-2,4-Dimethoxy-Phenyl)Chromen-4-One
CAS No.	6971-19-3
Molecular Formula	C₁₇H₁₃BrO₄
Molecular Weight	361.19 g/mol
Synonyms	5-Bromo-2',4'-dimethoxyflavone; 5-Bromo-2,4-dimethoxyphenyl-4-chromenone; 2-(5-Bromo-2,4-dimethoxyphenyl)-4H-chromen-4-one; 5-Bromo-2,4-dimethoxyflavone; Flavone, 5-bromo-2',4'-dimethoxy-; 2-(5-Bromo-2,4-dimethoxyphenyl)-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2,4-Dimethoxy-Phenyl)Chromen-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.