Description

2α-Methylandrosterone CAS NO 6961-54-2 is a synthetic steroid derivative of androsterone, characterized by its specific methyl group substitution at the 2-alpha position. This structural modification is significant for research into modulating hormonal activity and metabolic pathways. It serves as a critical intermediate and reference standard for pharmaceutical R&D, particularly in the study of steroid biochemistry and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of steroid compounds via HPLC, GC-MS, or other techniques.
• Biochemical Research: Employed in academic and industrial research to study androgen receptor interactions, enzyme inhibition, and metabolic steroid pathways.
• Metabolite Studies: Acts as a model compound or metabolite analog in pharmacokinetic and drug metabolism studies.
• Material Science Precursor: Potential use in the development of specialized materials or chiral catalysts derived from steroid frameworks.

Basic Information

Product Name	2α-Methylandrosterone
CAS No.	6961-54-2
Molecular Formula	C₂₀H₃₂O₂
Molecular Weight	304.47 g/mol
Synonyms	2α-Methyl-5α-androstan-3α-ol-17-one; 2α-Methylandrosterone; 2α-Methyl-3α-hydroxy-5α-androstan-17-one; 5α-Androstan-17-one, 3α-hydroxy-2α-methyl-; 2-Methylandrosterone; 2α-Methyl-3α-hydroxyetioallocholan-17-one; 2α-Methyl-5α-androstane-3α,17β-diol (related diol form)
EINECS	Contact for details

Quality Control

Our 2α-Methylandrosterone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and residual solvents, supporting its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.