Description

6,8-Dichloro-3H-Quinazolin-4-One is a versatile and high-value heterocyclic organic compound that serves as a critical synthetic intermediate. Its core quinazolinone scaffold, functionalized with chlorine atoms at specific positions, makes it a key building block for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its utility in constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting kinase inhibition, anticancer, and antimicrobial activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex quinazoline and fused heterocyclic compounds.
• Material Science: Investigated for potential applications in the creation of organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Biochemical Tool Compound: Serves as a starting material for synthesizing probes and inhibitors used in biochemical and pharmacological studies.

Basic Information

Product Name	6,8-Dichloro-3H-Quinazolin-4-One
CAS No.	6952-11-0
Molecular Formula	C8H4Cl2N2O
Molecular Weight	215.04 g/mol
Synonyms	6,8-Dichloro-4(3H)-quinazolinone; 6,8-Dichloro-4-hydroxyquinazoline; 4(3H)-Quinazolinone, 6,8-dichloro-; 6,8-Dichloroquinazolin-4(3H)-one; 6,8-Dichloro-3,4-dihydro-4-oxoquinazoline; 6,8-Dichloro-4-quinazolinol; 6,8-Dichloro-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 6,8-Dichloro-3H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.