Description

8-o-Acetylharpagide is a specialized iridoid glycoside compound, a key derivative of the bioactive constituents found in plants like *Harpagophytum procumbens* (Devil's Claw). This high-purity reference standard is critical for ensuring analytical accuracy and product quality in research and development. It is primarily utilized by the pharmaceutical, nutraceutical, and analytical chemistry industries for applications in method validation, phytochemical analysis, and the development of standardized botanical extracts.

Application

• Pharmaceutical Reference Standard: Serves as a certified primary standard for the identification, assay, and purity testing of Devil's Claw extracts and related products.
• Bioactivity and Pharmacological Research: Used in *in vitro* and *in vivo* studies to investigate anti-inflammatory, analgesic, and chondroprotective mechanisms of action.
• Nutraceutical Quality Control: Essential for the standardization and batch-to-batch consistency of commercial herbal supplements containing harpagoside and related iridoids.
• Analytical Method Development: A critical component for developing and validating HPLC, UPLC, and LC-MS/MS methods in analytical laboratories.
• Botanical Extract Characterization: Employed to fingerprint and quantify specific markers in complex plant matrices for authenticity and potency verification.
• Academic and Institutional Research: Supports fundamental research in natural product chemistry, phytochemistry, and biosynthetic pathway studies.

Basic Information

Product Name	8-o-Acetylharpagide
CAS No.	6926-14-3
Molecular Formula	C17H26O11
Molecular Weight	406.38 g/mol
Synonyms	8-O-Acetylharpagide; Acetylharpagide; 8-Acetylharpagide; (1S,4aS,5S,7S,7aS)-5-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-7-yl acetate; Harpagide 8-acetate; 8-O-Acetylharpagoside (common misnomer)
EINECS	Contact for details

Quality Control

Our 8-o-Acetylharpagide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.