Description

1-Cyano-1-Cyclopropanecarboxylic Acid is a versatile and high-value cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a nitrile functional group on the same carbon atom, makes it an indispensable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides with cyclopropane ring systems.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and functional polymers with tailored thermal and mechanical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Cyano-1-Cyclopropanecarboxylic Acid
CAS No.	6914-79-0
Molecular Formula	C5H5NO2
Molecular Weight	111.10 g/mol
Synonyms	Cyclopropanecarbonitrile, 1-carboxy-; 1-Carboxycyclopropanecarbonitrile; 1-Cyano-1-cyclopropanecarboxylic acid; 1-Cyano-1-cyclopropanecarboxylate; 1-Cyano-1-cyclopropanecarboxylic acid; 1-Cyano-1-cyclopropanecarboxylic acid; 1-Cyano-1-cyclopropanecarboxylic acid; 1-Cyano-1-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Cyano-1-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.