Description

(17S)-3β,8,12β,14β,17-Pentahydroxy-5α-Pregnan-20-One is a high-purity, multi-hydroxylated pregnane derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. Its complex stereochemistry and functional group array make it a valuable building block for the research and development of steroidal drugs and bioactive molecules. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel therapeutic agents or reference standards.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the production of steroidal APIs (Active Pharmaceutical Ingredients) and complex hormone analogs.
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and enzyme inhibition research.
• Fine Chemical Synthesis: Serves as a chiral building block for constructing complex natural products and specialized organic molecules.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of related steroid compounds.

Basic Information

Product Name	(17S)-3β,8,12β,14β,17-Pentahydroxy-5α-Pregnan-20-One
CAS No.	6875-17-8
Molecular Formula	C21H34O6
Molecular Weight	382.49 g/mol
Synonyms	3β,8,12β,14β,17-Pentahydroxy-5α-pregnan-20-one; 17S-Pentahydroxypregnanone; 5α-Pregnane-3β,8,12β,14β,17-pentol-20-one; (17S)-Pentahydroxypregnan-20-one; 6875-17-8; Pregnan-20-one, 3,8,12,14,17-pentahydroxy-, (3β,5α,8α,12β,14β,17S)-
EINECS	Contact for details

Quality Control

Our (17S)-3β,8,12β,14β,17-Pentahydroxy-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.