Description

Cyclobutanethiol CAS NO 6861-61-6 is a specialized organosulfur compound featuring a four-membered cyclobutane ring. This structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for introducing sulfur-containing functional groups. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel molecular architectures and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates requiring thiol or sulfide moieties.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclobutyl-thiol group can impart specific biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and as a precursor for heterocyclic compounds in material science research.
• Flavor and Fragrance Industry: Acts as a potential intermediate for synthesizing sulfur-containing aroma chemicals, contributing to complex scent profiles.
• Polymer Modification: Utilized as a chain-transfer agent or functional monomer to introduce sulfur groups into polymers, altering their physical and chemical properties.
• Organic Synthesis Building Block: A fundamental reagent for cycloaddition reactions, ring-opening transformations, and the construction of complex, strained-ring systems in academic and industrial research.

Basic Information

Product Name	Cyclobutanethiol
CAS No.	6861-61-6
Molecular Formula	C4H8S
Molecular Weight	88.17 g/mol
Synonyms	Cyclobutyl mercaptan; Cyclobutanethiol; Mercaptocyclobutane; Cyclobutylthiol; 1-Cyclobutylthiol; Cyclobutanethiol; Thiolane, tetrahydro-; Tetrahydrothiophene (Note: This is a structural isomer, often listed as a synonym); Cyclobutane thiol
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanethiol is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC), identity (IR), and specific impurity profiles. Our quality commitment ensures reliable consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, well-ventilated place. Recommended storage temperature is 2-8°C to minimize oxidation and degradation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.