Description

5-Chloro-2-Iodoaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of antimicrobial and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated aniline core provides specific biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as charge-transport molecules and ligands for metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Research & Development: A valuable tool for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	5-Chloro-2-Iodoaniline
CAS No.	6828-35-9
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	2-Iodo-5-chloroaniline; 5-Chloro-2-iodobenzenamine; 1-Amino-5-chloro-2-iodobenzene; Benzenamine, 5-chloro-2-iodo-; 5-Chloro-o-iodoaniline; 2-Amino-4-chloroiodobenzene; Aniline, 5-chloro-2-iodo-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Iodoaniline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.