Description

(9β,10α)-4-Chloro-Androst-4-Ene-3,17-Dione CAS NO 6765-84-0 is a high-purity steroidal intermediate, specifically a 4-chloro derivative of androstenedione. This compound is valued for its role as a key synthetic precursor in the production of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories and manufacturing facilities engaged in the synthesis of corticosteroids, anti-inflammatory agents, and other specialized therapeutic steroids. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potent corticosteroid drugs and other steroidal therapeutics.
• Research & Development: Used in medicinal chemistry for the discovery and development of new steroid-based compounds with targeted biological activity.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid APIs.
• Biochemical Research: Employed in studies investigating steroidogenesis, enzyme inhibition (e.g., aromatase, 5-alpha reductase), and hormone receptor interactions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized steroid derivatives not commercially available.

Basic Information

Item	Details
Product Name	(9β,10α)-4-Chloro-Androst-4-Ene-3,17-Dione
CAS No.	6765-84-0
Molecular Formula	C19H25ClO2
Molecular Weight	320.85 g/mol
Synonyms	4-Chloroandrost-4-ene-3,17-dione; 4-Chloroandrostenedione; 4-Chloro-AD; 4-Cl-AD; 4-Chloro-4-androstene-3,17-dione; (9β,10α)-4-Chloroandrost-4-ene-3,17-dione; 4-Chloroandrost-4-en-3,17-dione; NSC 113299
EINECS	Contact for details

Quality Control

Our (9β,10α)-4-Chloro-Androst-4-Ene-3,17-Dione is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.