Description

5-Hydroxy-3'-Methoxyflavone is a high-purity, synthetic flavonoid derivative of significant interest in advanced research and development. This compound matters for its role as a key intermediate and reference standard in the study of bioactive natural products and their synthetic analogs. Industries that need it include pharmaceutical R&D, nutraceutical development, and academic research focused on flavonoid chemistry and pharmacology.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and biological evaluation of novel therapeutic agents, particularly those targeting inflammation and oxidative stress.
• Nutraceutical & Cosmetic Ingredient Research: Investigated for its potential antioxidant and skin-protective properties in the development of advanced functional ingredients.
• Academic & Biochemical Research: Used as a pure chemical standard in studies of flavonoid metabolism, structure-activity relationships (SAR), and enzyme inhibition assays.
• Analytical Chemistry: Employed as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods to ensure accuracy in flavonoid quantification and identification.
• Chemical Synthesis: Acts as a versatile building block for the semi-synthesis of more complex flavonoid derivatives and analogs for commercial and research purposes.

Basic Information

Product Name	5-Hydroxy-3'-Methoxyflavone
CAS No.	6697-60-5
Molecular Formula	C₁₆H₁₂O₄
Molecular Weight	268.26 g/mol
Synonyms	3'-Methoxy-5-hydroxyflavone; 5-Hydroxy-3'-methoxy-2-phenyl-4H-chromen-4-one; Flavone, 5-hydroxy-3'-methoxy-; 5-Hydroxy-3'-methoxyflavonol (common name); 3'-Methoxy-5-hydroxy-2-phenyl-4H-1-benzopyran-4-one; 5-Hydroxy-3'-methoxy-2-phenylchromen-4-one
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-3'-Methoxyflavone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to light and air should be avoided. For long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.