Description

Destruxin A is a potent cyclic hexadepsipeptide mycotoxin produced by the entomopathogenic fungus *Metarhizium anisopliae*. This compound is of significant interest for its role as a highly specific bio-insecticide and for its unique biological activity in disrupting calcium ion channels in insect muscle cells. It serves as a critical research tool for scientists in agrochemical development, entomology, and cell biology, enabling the study of insect physiology and the discovery of novel pest control mechanisms.

Application

• Bio-Insecticide Research & Development: Primary tool for studying novel, environmentally friendly insecticidal agents and their modes of action.
• Entomological Studies: Used to investigate insect physiology, specifically muscle paralysis and calcium channel function in target pests.
• Agricultural Biotechnology: Serves as a reference standard and active ingredient prototype for developing next-generation biopesticides.
• Cell Biology & Toxicology: Employed in research on cellular ion transport mechanisms and specific toxin-cell interactions.
• Academic & Institutional Research: Essential for universities and research institutes focusing on mycology, pest management, and natural product chemistry.
• Pharmaceutical Probe Discovery: Investigated for its potential in modulating biological pathways relevant to human disease research.

Basic Information

Item	Detail
Product Name	Destruxin A
CAS No.	6686-70-0
Molecular Formula	C30H45N5O9
Molecular Weight	619.71 g/mol
Synonyms	Destruxin A; Cyclo[L-Phe-D-Hydroxyisovaleryl-L-Pro-L-Ile-D-Hydroxyisovaleryl-L-MeVal]; NSC 267213; [1S-[1R*,2S*(2S*,3R*),4R*]]-4-[[2-[[2-[(2S)-2-[[(2R)-2-Hydroxy-3-methyl-1-oxobutyl]amino]-1-oxopropyl]-4-methyl-1-oxopentyl]amino]-1-[(1S)-1-methylpropyl]-2-oxoethyl]amino]-5-methyl-2-(1-methylethyl)-7-oxo-1,6-diazacyclododec-4-ene-1-acetic Acid
EINECS	Contact for details

Quality Control

Our Destruxin A is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC and MS, are validated to provide reliable data for critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.